1011_細胞膜訊息傳導專題研究(一)
上課期間:從 即日起 到 無限期
課程介紹
課程安排
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Curvature recognition and force generation in phagocytosis
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Localised PtdIns(3,4,5)P3 or PtdIns(3,4)P2 at the phagocytic cup is required for both phagosome closure and Ca2+ signalling in HL60 neutrophils
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Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes
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Myo1c binds phosphoinositides through a putative PH domain
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Phosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxis
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Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis
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Expression of Y53A-actin in Dictyostelium disrupts the cytoskeleton and inhibits intracellular and intercellular chemotactic signaling
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Myosin X is a downstream effector of PI(3)K during phagocytosis
教師 / 陳俊霖